Research Group Tumor Targeting
For targeted imaging and therapy of cancer, surface proteins of tumor cells can be used as targets for probes with high affinity and specificity. This approach, known as tumor targeting, involves identifying molecular targets in tumors, developing probes for nuclear imaging/therapy of gastrointestinal tumors, and demonstrating the principle in the whole organism.
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Research focus:
- Identification of novel tumor-specific target molecules
- Target validation of peptide GPCRs and other cell surface/matrix proteins in gastrointestinal tumors
- Development of novel peptide conjugates for tumor targeting in the gastrointestinal tract
- Optimization of peptide guide structures
- Development of near-infrared fluorescence imaging techniques
- PET diagnostics and radioligand therapy
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